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soul trial oral semaglutide cardiovascular outcomes results 2025 Oral Semaglutide Reduces CV Events in T2DM – SOUL Trial (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine 🧪 T2DM + ASCVD/CKD 💊 Oral semaglutide 14 mg vs placebo 📉

Marsoni M251S
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4.8 ★★★★★
Based on 321 reviews
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Verified Purchase
Jennifer Donnelly
Cuba, US
★★★★★ 5
Pleasantly surprised
I’m two jars in and love it. I do use Botox, retinol, a good face wash, wash moisturize twice daily, etc etc. I struggle with moisturizer because I’m prone to breakouts. Idk what it is about this one but my skin loves it. It feels refreshed and soft. Added bonus, my eyebrows and lashes have gotten longer and darker quick! Obviously we all respond differently to products but I’ll be keeping this in my rotation
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 3, 2026
D
Verified Purchase
Deb from the Ridge
Lake Worth, US
★★★★★ 5
A thick and rich cream that smooths on nicely!
So I jumped on the Korean skincare bandwagon and decided to purchase some of the DR MELAXIN Products to try! I read many good reviews and decided it was worth the money. This first product is the Dr Melaxin Calcium cemenrete calcium volume cream. It comes in a 1.76 ounce glass jar. On the label there is a lot of word descriptions so I will add a few: Ex volume firming, rebornic 10,000 ppm hydrolyzed elastin and collagen extract. I have photographed label for viewing. The directions indicate to "apply a small amount of cream onto your face especially around the under-eye area". I found the cream thick and rich and I used it in addition to another Dr Melaxin neck and face product so I concentrated on only neck and under eye area. It is neutral in scent and is very thick so it feels like it is absorbing nicely. I have been using it for about a month now and have definitely noticed some improvement in the neck area so i will continue to use and layer with other products. I do recommend this line as the ingredients seem effective so far!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 4, 2026
E
Verified Purchase
E.R.
San Leandro, US
★★★★★ 5
Good product for face.
Great product. Works well with decreasing lines in face after half is used and with the serum. It does leave somewhat of a sticky (not grimy) texture which is uncomfortable if using at night.
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Reviewed in the United States on June 1, 2026
E
Verified Purchase
E. L. Phipps
Lake Worth, US
★★★★★ 4
Loose under eye skin tightened and brightened!
I love this cream! It makes a huge difference in the strength of the skin under my eyes and smooths the look and feel of the wrinkled skin under my eyes. It brightens my under eye circles. I gave 4 stars because if you use too much it will start to roll off almost like skin does when it sheds or when you exfoliate. I use less now and it’s perfect.
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Reviewed in the United States on May 3, 2026
E
Verified Purchase
Emma DG
Draper, US
★★★★★ 5
Working on Deep Wrinkles Great Results
I really like this product, it’s been working well on deeper wrinkles, especially on my forehead and around my smile lines. With consistent use, I can see a noticeable improvement in how my skin looks. The texture feels hydrating and smooth, and it absorbs nicely without feeling heavy. It leaves my skin feeling softer and more refreshed after each use. I also like that it helps with overall skin appearance, making it look more even and a bit more radiant. Minor note: Results take consistency, so it’s best to use it regularly to see the full effect. Overall, this is a great product for targeting fine lines and deeper wrinkles. Hydrating, easy to use, and delivers visible improvements over time.
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Reviewed in the United States on April 15, 2026

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